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Clinical trials for Heart Ventricle

The European Union Clinical Trials Register   allows you to search for protocol and results information on:
  • interventional clinical trials that were approved in the European Union (EU)/European Economic Area (EEA) under the Clinical Trials Directive 2001/20/EC
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    • EU/EEA interventional clinical trials approved under or transitioned to the Clinical Trial Regulation 536/2014 are publicly accessible through the
    Clinical Trials Information System (CTIS).

    The EU Clinical Trials Register currently displays   43881   clinical trials with a EudraCT protocol, of which   7295   are clinical trials conducted with subjects less than 18 years old.   The register also displays information on   18700   older paediatric trials (in scope of Article 45 of the Paediatric Regulation (EC) No 1901/2006).

    Phase 1 trials conducted solely on adults and that are not part of an agreed paediatric investigation plan (PIP) are not publicly available (see Frequently Asked Questions ).  
     
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    125 result(s) found for: Heart Ventricle. Displaying page 1 of 7.
    1  2  3  4  5  6  7  Next»
    EudraCT Number: 2011-001187-21 Sponsor Protocol Number: SCRM-001 Start Date*: 2011-11-28
    Sponsor Name:University of Zurich
    Full Title: A Phase I/II, Open Monocentric Study To Evaluate The Safety And Efficacy Of An Autologous Tissue-Engineered Vascular Graft In Peadiatric Patients Requiring Reconstruction Of Right Ventricle Outflow...
    Medical condition: functional single ventricle physiology functional single left ventricle functional single right ventricle functional single biventricle
    Disease: Version SOC Term Classification Code Term Level
    14.0 10010331 - Congenital, familial and genetic disorders 10040729 Single ventricle LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: DE (Temporarily Halted)
    Trial results: View results
    EudraCT Number: 2007-002688-28 Sponsor Protocol Number: 66/2007/U/Sper Start Date*: 2007-05-22
    Sponsor Name:AZIENDA OSPEDALIERA DI BOLOGNA POLICLINICO S. ORSOLA M. MALPIGHI
    Full Title: Pilot study on the short-term effects of Sildenafil on hemodynamic response to exercise and exercise capacity in Fontan patients
    Medical condition: congenital heart disease
    Disease: Version SOC Term Classification Code Term Level
    6.1 10045545 PT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2007-001787-71 Sponsor Protocol Number: CCB-CRC-07-01 Start Date*: 2008-02-11
    Sponsor Name:Charité - Universitätsmedizin Berlin
    Full Title: The influence of Rimonabant induced cannabinoid receptor blocking on the mass and function of the left ventricle in patients with abdominal adiposity
    Medical condition: Adiposity is another risk factor for developing cardiac insufficiency and myocardial hypertrophy. Probably the volume loading of the left ventricle, systemic inflammation, the fatty degeneration of...
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: DE (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2006-002262-19 Sponsor Protocol Number: CVAL489ANL09 Start Date*: 2006-08-07
    Sponsor Name:Novartis Pharma B.V.
    Full Title: Angiotensin II receptor blockers in patients with systemic right ventricle.
    Medical condition: Systemic right ventricle due to total transposition of the great arteries or congenitally corrected transposition of the great arteries
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: NL (Completed)
    Trial results: View results
    EudraCT Number: 2016-004291-21 Sponsor Protocol Number: 33IC30_166855 Start Date*: 2018-01-15
    Sponsor Name:Insel Gruppe AG - Inselspital Universitätsklinik für Kardiologie
    Full Title: Effect of phosphodiesterase-5 inhibition with Tadalafil on SystEmic Right VEntricular size and function – a multi-center, double-blind, randomized, placebo-controlled clinical trial – SERVE Trial
    Medical condition: Adults with congenital heart disease (CHD) and a right ventricle (RV) in subaortic (systemic) position.
    Disease:
    Population Age: Adults Gender: Male, Female
    Trial protocol: AT (Completed)
    Trial results: View results
    EudraCT Number: 2015-001560-19 Sponsor Protocol Number: CSCC-ASC2 Start Date*: 2015-06-29
    Sponsor Name:Department of Cardiology, Rigshospitalet
    Full Title: Allogeneic adipose tissue-derived stromal/stem cell therapy in patients with ischemic heart disease and heart failure
    Medical condition: Ischemic heart disease and heart failure
    Disease: Version SOC Term Classification Code Term Level
    18.0 100000004849 10019279 Heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Ongoing)
    Trial results: View results
    EudraCT Number: 2017-005077-39 Sponsor Protocol Number: BBLOQ-2017 Start Date*: 2018-06-12
    Sponsor Name:Instituto de Investigación Sanitaria INCLIVA
    Full Title: Betablockers Withdrawal in Patients with Heart Failure with Preserved Ejection Fraction and Chronotropic Incompetence: Effect on Functional Capacity and life quality
    Medical condition: Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10019280 Heart failures HLGT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-005898-29 Sponsor Protocol Number: RRK2962 Start Date*: 2008-07-04
    Sponsor Name:University Hospital Birmingham
    Full Title: The effect of bosentan, a selective endothelin antagonist, on cardiovascular performance in patients with a Fontan circulation
    Medical condition: Patients with a Fontan circulation (that is they have had a Fontan operation for a functionally univentricular heart)
    Disease: Version SOC Term Classification Code Term Level
    9.1 10045545 Univentricular heart LLT
    9.1 10065950 Cavopulmonary anastomosis LLT
    9.1 10037456 Pulmonary vascular resistance abnormality LLT
    Population Age: Adults Gender: Male, Female
    Trial protocol: GB (Completed)
    Trial results: (No results available)
    EudraCT Number: 2018-002821-45 Sponsor Protocol Number: AC-055H302 Start Date*: 2019-03-05
    Sponsor Name:Actelion Pharmaceuticals Ltd
    Full Title: Prospective, multi-center, single-arm, open-label long-term study assessing the safety, tolerability, and effectiveness of macitentan in Fontan-palliated adult and adolescent subjects
    Medical condition: Congenital Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10045545 Univentricular heart PT
    20.0 10042613 - Surgical and medical procedures 10065950 Cavopulmonary anastomosis PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: FR (Completed) DE (Completed) GB (GB - no longer in EU/EEA) DK (Completed) PL (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2021-005394-66 Sponsor Protocol Number: ESR-20-21070 Start Date*: 2022-02-21
    Sponsor Name:AZIENDA OSPEDALIERA UNIVERSITARIA SENESE
    Full Title: Effects of Dapagliflozin on cardiac deformation and clinical outcomes in heart failure with reduced and mildly reduced ejection fraction
    Medical condition: heart failure with left ventricular ejection fraction <50%
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10024102 Left cardiac failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2015-002610-76 Sponsor Protocol Number: 39039039CHD3001/BAY59-7939-18226 Start Date*: 2016-09-21
    Sponsor Name:Janssen-Cilag International N.V
    Full Title: A Prospective, Open-Label, Active-Controlled Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of Rivaroxaban for Thromboprophylaxis in Pediatric Subjects 2 to 8 Years ...
    Medical condition: thromboprophylaxis
    Disease: Version SOC Term Classification Code Term Level
    19.0 100000004850 10040729 Single ventricle LLT
    Population Age: Children, Under 18 Gender: Male, Female
    Trial protocol: BE (Completed) FR (Completed) ES (Completed) NL (Completed)
    Trial results: View results
    EudraCT Number: 2013-001659-10 Sponsor Protocol Number: S55481 Start Date*: 2013-08-08
    Sponsor Name:UZLeuven
    Full Title: Acute effects of Sildenafil on the hemodynamics, Right Ventricle performance and cyclic GMP concentration in Heart failure patients with preserved left ventricular ejection fraction and patients af...
    Medical condition: To investigate acute effects of sildenafil on cardiac hemodynamics, right ventricle performance and cGMP concentrations in heart failure patients with preserved ejection fraction and patients after...
    Disease: Version SOC Term Classification Code Term Level
    16.0 100000004855 10037406 Pulmonary hypertension secondary LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: BE (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2019-000661-20 Sponsor Protocol Number: ICO Start Date*: 2019-05-31
    Sponsor Name:Vilnius University Hospital Santaros klinikos
    Full Title: Ivabradine to prevent anthracycline-induced cardiotoxicity: a prospective randomized open label clinical trial.
    Medical condition: Cancers treated with anthracyclines: leukemias, limphomas, breast, stomach, uterine, ovarian, lung.
    Disease:
    Population Age: Elderly Gender: Male, Female
    Trial protocol: LT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2005-002580-85 Sponsor Protocol Number: 3d Start Date*: 2005-08-08
    Sponsor Name:Rigshospitalet
    Full Title: Acute haemodynanic effects of Treatment with ACE inhibitores in patients with severe Aortic Stenosis
    Medical condition: Aortic valve stenosis is a reduction of the aortic valve orifice to a degree where emptying of the left ventricule is compromised. The two major causes for aortic valve stenosis is calcific valve d...
    Disease:
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: DK (Completed)
    Trial results: (No results available)
    EudraCT Number: 2009-015826-13 Sponsor Protocol Number: Q-10 Start Date*: 2010-10-07
    Sponsor Name:PROF. TIZIANO GHERLI
    Full Title: THE USE OF COENZYME Q 10 BEFORE HEART SURGERY IN ELDERLY PATIENTS.
    Medical condition: Patients (male or female) aged > 70 years, clinically stable, with a diagnosis of severe aortic stenosis with indication to surgery based on echocardiography and left ventricle angiography.
    Disease: Version SOC Term Classification Code Term Level
    12.0 10049194 Stable angina pectoris LLT
    Population Age: Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: (No results available)
    EudraCT Number: 2005-001306-87 Sponsor Protocol Number: CANc/CHF14/TIF Start Date*: 2005-06-13
    Sponsor Name:TAKEDA
    Full Title: EFFECTS OF CANDESARTAN CILEXETIL VS STANDARD THERAPY ON SERUM LEVELS OF BRAIN NATRIURETIC PEPTIDE IN PATIENTS SUFFERING FROM CHRONIC HEART FAILURE WITH DEPRESSED AND PRESERVED SYSTOLIC FUNCTION
    Medical condition: CHRONIC HEART FAILURE
    Disease: Version SOC Term Classification Code Term Level
    9.1 10024120 Left ventricular failures HLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: IT (Prematurely Ended)
    Trial results: View results
    EudraCT Number: 2019-003902-29 Sponsor Protocol Number: EASI-Child Start Date*: 2020-04-30
    Sponsor Name:IRCCS, OSPEDALE PEDIATRICO BAMBINO GESÙ DI ROMA
    Full Title: Early Administration of Ivabradine in Children with Heart Failure.
    Medical condition: Acute hearth failure in dilated cardiomyopathy.
    Disease: Version SOC Term Classification Code Term Level
    20.0 10007541 - Cardiac disorders 10007541 Cardiac disorders SOC
    Population Age: Infants and toddlers, Children, Adolescents, Under 18 Gender: Male, Female
    Trial protocol: IT (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2016-003320-23 Sponsor Protocol Number: AC-055H301 Start Date*: 2017-10-11
    Sponsor Name:Actelion Pharmaceuticals Ltd
    Full Title: Prospective, multi-center, double-blind, randomized, placebo-controlled, parallel-group study assessing the efficacy and safety of macitentan in Fontan-palliated adult and adolescent subjects.
    Medical condition: Congenital Heart Failure
    Disease: Version SOC Term Classification Code Term Level
    20.0 10010331 - Congenital, familial and genetic disorders 10045545 Univentricular heart PT
    21.1 10042613 - Surgical and medical procedures 10065950 Cavopulmonary anastomosis PT
    Population Age: Adolescents, Under 18, Adults Gender: Male, Female
    Trial protocol: GB (GB - no longer in EU/EEA) DE (Completed) DK (Completed) FR (Completed) PL (Completed) IE (Completed) CZ (Completed)
    Trial results: View results
    EudraCT Number: 2022-002688-31 Sponsor Protocol Number: ICOR-2022-04-LEVOMEMS Start Date*: 2023-01-25
    Sponsor Name:Germans Trias i Pujol Health Research Institute
    Full Title: LEVO-MEMS: COMPARISION OF THE HAEMODINAMIC PROFILE OF DOBUTAMIN AND LEVOSIMENDAN IN THE CURRENT THERAPEUTICAL CONTEXT
    Medical condition: Heart failure patients with depressed left ventricular ejection fraction
    Disease: Version SOC Term Classification Code Term Level
    20.0 100000004849 10019279 Heart failure LLT
    20.0 100000004849 10010684 Congestive heart failure LLT
    20.0 100000004849 10019284 Heart failure, congestive LLT
    20.0 100000004849 10024106 Left heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Ongoing)
    Trial results: (No results available)
    EudraCT Number: 2011-001674-25 Sponsor Protocol Number: 1684-H-295 Start Date*: 2012-05-25
    Sponsor Name:Francisco J. González Vílchez
    Full Title: Evaluation of the efficacy of sildenafil on the functional capacity of patients with heart failure with preserved ejection fraction. A randomized, double blind, parallel group and placebo-controlle...
    Medical condition: Heart failure with preserved ejection fraction.
    Disease: Version SOC Term Classification Code Term Level
    14.1 10007541 - Cardiac disorders 10069211 Diastolic heart failure LLT
    Population Age: Adults, Elderly Gender: Male, Female
    Trial protocol: ES (Prematurely Ended)
    Trial results: (No results available)
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    The status and protocol content of GB trials is no longer updated since 1 January 2021. For the UK, as of 31 January 2021, EU Law applies only to the territory of Northern Ireland (NI) to the extent foreseen in the Protocol on Ireland/NI. Legal notice
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